| 翻訳と辞書 |
| protein tertiary structure ： ウィキペディア英語版 |
protein tertiary structure
The term protein tertiary structure refers to a protein's geometric shape. The tertiary structure will have a single polypeptide chain "backbone" with one or more protein secondary structures, the protein domains. Amino acid side chains may interact and bond in a number of ways. The interactions and bonds of side chains within a particular protein determine its tertiary structure. The protein tertiary structure is defined by its atomic coordinates. These coordinates may refer either to a protein domain or to the entire tertiary structure.〔Branden C. and Tooze J. "Introduction to Protein Structure" Garland Publishing, New York. 1990 and 1991.〕 A number of tertiary structures may fold into a quaternary structure.〔Kyte, J. "Structure in Protein Chemistry." Garland Publishing, New York. 1995. ISBN 0-8153-1701-8〕
== History ==
The science of the tertiary structure of proteins has progressed from one of hypothesis to one of detailed definition. Although Emil Fischer had suggested proteins were made of polypeptide chains and amino acid side chains, it was Dorothy Maud Wrinch who incorporated geometry into the prediction of protein structures. Wrinch demonstrated this with the ''Cyclol'' model, the first prediction of the structure of a globular protein.〔Senechal M. ("I died for beauty: Dorothy Wrinch and the cultures of science." ) Oxford University Press, 2012. Chapter 14. ISBN 0-19-991083-9, 9780199910830. Accessed at Google Books 8 December 2013.〕 Contemporary methods are able to determine, without prediction, tertiary structures to within 5 Å (0.5 nm) for small proteins (<120 residues) and, under favorable conditions, confident secondary structure predictions.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
■ウィキペディアで「protein tertiary structure」の詳細全文を読む
スポンサード リンク
| 翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|